Enzyme Details

EC Classification

3.4.14.5

Enzyme name
(recommended)

dipeptidyl-peptidase IV

Alternative names

dipeptidyl aminopeptidase IV
Xaa-Pro-dipeptidyl-aminopeptidase
Gly-Pro naphthylamidase
postproline dipeptidyl aminopeptidase IV
lymphocyte antigen CD26
glycoprotein GP110
dipeptidyl peptidase IV
glycylproline aminopeptidase
glycylproline aminopeptidase
X-prolyl dipeptidyl aminopeptidase
pep X
leukocyte antigen CD26
glycylprolyl dipeptidylaminopeptidase
dipeptidyl-peptide hydrolase
glycylprolyl aminopeptidase
dipeptidyl-aminopeptidase IV
DPP IV/CD26
amino acyl-prolyl dipeptidyl aminopeptidase
T cell triggering molecule Tp103
X-PDAP

Classification

Hydrolases

Acting on peptide bonds (peptide hydrolases)

Dipeptidyl-peptidases and tripeptidyl-peptidases

Catalyses reactions

H2O + Gly-Pro-4-Nitroanilide <-> 4-Nitroaniline + Gly-Pro

H2O + Ala-Pro-7-amido-4-methylcoumarin <-> Ala-Pro + 7-Amino-4-methylcoumarin

H2O + His-Pro-Leu <-> L-Leucine + His-Pro

H2O + His-Pro-Tyr <-> L-Tyrosine + His-Pro

H2O + Gly-Pro-Ala <-> L-Alanine + Gly-Pro

H2O + Arg-Pro-4-Nitroanilide <-> 4-Nitroaniline + Arg-Pro

H2O + Ala-Ala-4-Nitroanilide <-> 4-Nitroaniline + Ala-Ala