Enzyme Details

 EC Classification 3.4.14.5
 Enzyme name
(recommended)
dipeptidyl-peptidase IV
 Alternative names dipeptidyl aminopeptidase IV
Xaa-Pro-dipeptidyl-aminopeptidase
Gly-Pro naphthylamidase
postproline dipeptidyl aminopeptidase IV
lymphocyte antigen CD26
glycoprotein GP110
dipeptidyl peptidase IV
glycylproline aminopeptidase
glycylproline aminopeptidase
X-prolyl dipeptidyl aminopeptidase
pep X
leukocyte antigen CD26
glycylprolyl dipeptidylaminopeptidase
dipeptidyl-peptide hydrolase
glycylprolyl aminopeptidase
dipeptidyl-aminopeptidase IV
DPP IV/CD26
amino acyl-prolyl dipeptidyl aminopeptidase
T cell triggering molecule Tp103
X-PDAP
 Classification
Hydrolases
Acting on peptide bonds (peptide hydrolases)
Dipeptidyl-peptidases and tripeptidyl-peptidases
 Catalyses reactions
H2O + Gly-Pro-4-Nitroanilide <-> 4-Nitroaniline + Gly-Pro
Ala-Pro-7-Amino-4-methylcoumarin <-> NH2Mec + Ala-Pro
H2O + His-Pro-Leu <-> L-Leucine + His-Pro
H2O + His-Pro-Tyr <-> L-Tyrosine + His-Pro
H2O + Gly-Pro-Ala <-> L-Alanine + Gly-Pro
H2O + Arg-Pro-4-Nitroanilide <-> 4-Nitroaniline + Arg-Pro
H2O + Ala-Ala-4-Nitroanilide <-> 4-Nitroaniline + Ala-Ala
H2O + Leu-Ala-Pro <-> L-Proline + Leu-Ala
H2O + Ala-Pro-7-Amino-4-trifluoromethylcoumarin <-> Ala-Pro + 7-Amino-4-trifluoromethylcoumarin
H2O + Ala-Pro-4-Nitroanilide <-> 4-Nitroaniline + Ala-Pro
Ala-Pro-7-amido-4-trifluoromethylcoumarin <-> Ala-Pro + 7-Amino-4-trifluoromethylcoumarin
H2O + Gly-Pro-4-Nitroanilide p-toluenesulfonate <-> 4-Nitroaniline + Gly-Pro
H2O + Gly-Pro-2-naphthylamide <-> 2-Naphthylamine + Gly-Pro
H2O + Gly-Pro-4-methoxy-2-naphthylamide <-> Gly-Pro + 4-Methoxy-2-naphthylamine
H2O + Ala-Ala-2-naphthylamide <-> 2-Naphthylamine + Ala-Ala
H2O + Phe-Pro-2-naphthylamide <-> 2-Naphthylamine + Phe-Pro
H2O + Lys-Pro-4-methoxy-2-naphthylamide <-> Lys-Pro + 4-Methoxy-2-naphthylamine
H2O + Asp-Pro-4-Nitroanilide <-> 4-Nitroaniline + Asp-Pro
 External links Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop


View all entries for EC Class: 3.4.14.5



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