Enzyme Details

EC Classification

3.4.11.1

Enzyme name
(recommended)

leucyl aminopeptidase

Alternative names

leucine aminopeptidase
leucyl peptidase
peptidase S
cytosol aminopeptidase
cathepsin III
L-leucine aminopeptidase
leucinaminopeptidase
leucinamide aminopeptidase
FTBL proteins
proteinates FTBL
aminopeptidase II
aminopeptidase III
aminopeptidase I

Classification

Hydrolases

Acting on peptide bonds (peptide hydrolases)

Aminopeptidases

Catalyses reactions

H2O + L-Cysteinylglycine <-> Glycine + L-Cysteine

H2O + L-Leucylglycine <-> Glycine + L-Leucine

H2O + Met-Gly <-> Glycine + L-Methionine

H2O + Ser-Gly <-> Glycine + L-Serine

H2O + L-Leucinyl-p-nitroanilide <-> L-Leucine + 4-Nitroaniline

H2O + Cys-Leu <-> L-Leucine + L-Cysteine

H2O + Leu-Cys <-> L-Leucine + L-Cysteine

H2O + Glycyl-leucine <-> Glycine + L-Leucine

H2O + Arg-Leu <-> L-Leucine + Arginine

H2O + Leu-Leu <-> 2 L-Leucine

H2O + Gly-Gly <-> 2 Glycine

H2O + Arg-Gly <-> Glycine + Arginine

H2O + Arg-Gly-Phe <-> Arginine + Gly-Phe

H2O + Arg-Gly-Asp <-> Arginine + Glycyl-L-aspartate

H2O + Leu-Gly-Gly <-> Leucine + Gly-Gly

H2O + Leu-p-nitroanilide <-> 4-Nitroaniline + Leucine

H2O + Leu-Tyr <-> L-Leucine + L-Tyrosine

H2O + Met-Leu-Gly <-> L-Methionine + L-Leucylglycine

H2O + L-Leucyl-beta-naphthylamide <-> L-Leucine + 2-Naphthylamine

H2O + L-Alanylglycine <-> Glycine + L-Alanine

H2O + Leu-Gly-Gly <-> L-Leucine + Gly-Gly

H2O + L-Leucinamide <-> L-Leucine + NH3

H2O + Arg-4-methylcoumaryl-7-amide <-> L-Arginine + 7-Amino-4-methylcoumarin

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 3.4.11.1