Enzyme Details

EC Classification

3.2.1.49

Enzyme name
(recommended)

alpha-N-acetylgalactosaminidase

Alternative names

alpha-N-acetyl-D-galactosaminide N-acetylgalactosaminohydrolase
alpha-acetylgalactosaminidase
N-acetyl-alpha-D-galactosaminidase
N-acetyl-alpha-galactosaminidase
alpha-NAGAL
alpha-NAGA
alpha-GalNAcase

Classification

Hydrolases

Glycosidases

Hydrolysing O-glycosyl compounds

Catalyses reactions

N-Acetylgalactosamine + Globoside <-> H2O + N-Acetyl-D-galactosaminyl-N-Acetyl-D-galactosaminyl-1,3-D-galactosyl-1,4-D-galactosyl-1,4-D-glucosylceramide

H2O + 4-Methylumbelliferyl-alpha-D-galactoside <-> alpha-D-Galactose + 4-Methylumbelliferone

H2O + o-Nitrophenyl-alpha-N-acetylgalactosaminide <-> N-Acetylgalactosamine + o-Nitrophenol

H2O + Globotriaose <-> alpha-D-Galactose + beta-D-Galactosyl-1,4-beta-D-glucopyranose

H2O + Globopentaose <-> N-Acetylgalactosamine + N-Acetyl-D-galactosaminyl-1,3-D-galactosyl-1,4-D-galactosyl-1,4-D-glucopyranose

H2O + Trihexosylceramide <-> alpha-D-Galactose + beta-D-Galactosyl-1,4-beta-D-glucosylceramide

H2O + p-Nitrophenyl-N-acetyl-alpha-D-galactosaminide <-> N-Acetylgalactosamine + p-Nitrophenol

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 3.2.1.49