Enzyme Details

 EC Classification 3.1.3.48
 Enzyme name
(recommended)
protein-tyrosine-phosphatase
 Alternative names protein-tyrosine-phosphate phosphohydrolase
phosphotyrosine phosphatase
phosphoprotein phosphatase (phosphotyrosine)
phosphotyrosine histone phosphatase
protein phosphotyrosine phosphatase
tyrosylprotein phosphatase
phosphotyrosine protein phosphatase
phosphotyrosylprotein phosphatase
tyrosine O-phosphate phosphatase
PPT-phosphatase
PTPase
[phosphotyrosine]protein phosphatase
PTP-phosphatase
 Classification
Hydrolases
Acting on ester bonds
Phosphoric monoester hydrolases
 Catalyses reactions
H2O + Protein tyrosine phosphate <-> Phosphate + Protein tyrosine
H2O + 4-Nitrophenyl phosphate <-> Phosphate + p-Nitrophenol
H2O + beta-Naphthyl phosphate <-> Phosphate + beta-Naphthol
H2O + Phenolic phosphate <-> Phosphate + Phenol
H2O + 8-Fluoro-4-methylumbelliferyl phosphate <-> Phosphate + 8-Fluoro-4-methylumbelliferone
H2O + 6-Fluoro-4-methylumbelliferyl phosphate <-> Phosphate + 6-Fluoro-4-methylumbelliferone
H2O + 6,8-Difluoro-4-methylumbelliferyl phosphate <-> Phosphate + 6,8-Difluoro-4-methylumbelliferone
H2O + 5-Fluoro-4-methylumbelliferyl phosphate <-> Phosphate + 5-Fluoro-4-methylumbelliferone
H2O + 4-Trifluoromethylphenyl phosphate <-> Phosphate + 4-Trifluoromethylphenol
H2O + 4-Methylumbelliferyl phosphate <-> Phosphate + 4-Methylumbelliferone
H2O + 4-Cyanophenyl phosphate <-> Phosphate + 4-Cyanophenol
H2O + 4-Chlorophenyl phosphate <-> Phosphate + 4-Chlorophenol
H2O + 3-O-Methylfluorescein phosphate <-> Phosphate + 3-O-Methylfluorescein
H2O + 2-Chloro-4-nitrophenyl phosphate <-> Phosphate + 2-Chloro-4-nitrophenol
H2O + 3-Chlorophenyl phosphate <-> Phosphate + 3-Chlorophenol
H2O + 3-Nitrophenyl phosphate <-> Phosphate + 3-Nitrophenol
H2O + 4-Ethylphenyl phosphate <-> Phosphate + 4-Ethylphenol
H2O + 4-Fluorophenyl phosphate <-> Phosphate + p-Fluorophenol
H2O + Phosphotyrosine <-> Phosphate + Tyrosine
H2O + Proteine tyrosine phosphate <-> Phosphate + Protein tyrosine
((IFNRJ2_activated)(SHP2)) <-> IFNRJ2 + SHP2
H2O + L-Phosphotyrosine <-> Phosphate + L-Tyrosine
H2O + Adenosine 2'-phosphate <-> Phosphate + Adenosine
H2O + Protein tyrosine diphosphate <-> 2 Phosphate + Protein tyrosine
H2O + P-Erk2 <-> Phosphate + Erk2
 External links Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop


View all entries for EC Class: 3.1.3.48



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