Enzyme Details

 EC Classification 2.7.1.74
 Enzyme name
(recommended)
deoxycytidine kinase
 Alternative names NTP:deoxycytidine 5'-phosphotransferase
deoxycytidine kinase (phosphorylating)
2'-deoxycytidine kinase
Ara-C kinase
arabinofuranosylcytosine kinase
deoxycytidine-cytidine kinase
 Classification
Transferases
Transferring phosphorous-containing groups
Phosphotransferases with an alcohol group as acceptor
 Catalyses reactions
ATP + Adenosine <-> ADP + AMP
ATP + Deoxyadenosine <-> ADP + dAMP
ATP + Deoxyguanosine <-> ADP + dGMP
NTP + 2'-Deoxycytidine <-> dCMP + NDP
ATP + 2'-Deoxycytidine <-> ADP + dCMP
ATP + Cytarabine <-> ADP + 1-beta-D-Arabinofuranosylcytosine 5'-monophosphate
ATP + Zalcitabine <-> ADP + L-ddCMP
ATP + L-2'-Deoxycarbocyclic guanosine <-> ADP + L-2'-Deoxycarbocyclic guanosine 5'-phosphate
ATP + D-2'-Deoxycarbocyclic guanosine <-> ADP + D-2'-Deoxycarbocyclic guanosine 5'-phosphate
ATP + Vidarabine <-> ADP + 9-beta-D-Arabinofuranosyladenine 5'-monophosphate
GTP + 2'-Deoxycytidine <-> dCMP + GDP
CTP + 2'-Deoxycytidine <-> dCMP + CDP
ATP + Cytidine <-> ADP + CMP
ATP + Gemcitabine <-> ADP + Gemcitabine monophosphate
 External links Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop


View all entries for EC Class: 2.7.1.74



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