Enzyme Details

EC Classification

2.6.1.1

Enzyme name
(recommended)

aspartate transaminase

Alternative names

L-aspartate:2-oxoglutarate aminotransferase
glutamic-oxaloacetic transaminase
glutamic-aspartic transaminase
transaminase A
AAT
AspT
2-oxoglutarate-glutamate aminotransferase
aspartate alpha-ketoglutarate transaminase
aspartate aminotransferase
aspartate-2-oxoglutarate transaminase
aspartic acid aminotransferase
aspartic aminotransferase
aspartyl aminotransferase
AST
glutamate-oxalacetate aminotransferase
glutamate-oxalate transaminase
glutamic-aspartic aminotransferase
glutamic-oxalacetic transaminase
glutamic oxalic transaminase
GOT (enzyme)
L-aspartate transaminase
L-aspartate-alpha-ketoglutarate transaminase
L-aspartate-2-ketoglutarate aminotransferase
L-aspartate-2-oxoglutarate aminotransferase
L-aspartate-2-oxoglutarate-transaminase
L-aspartic aminotransferase
oxaloacetate-aspartate aminotransferase
oxaloacetate transferase
aspartate:2-oxoglutarate aminotransferase
glutamate oxaloacetate transaminase

Classification

Transferases

Transferring nitrogenous groups

Transaminases (aminotransferases)

Catalyses reactions

L-Alanine + 2-Oxoglutarate <-> Pyruvate + L-Glutamate

L-Aspartate + 2-Oxoglutarate <-> L-Glutamate + Oxaloacetate

L-Tryptophan + 2-Oxoglutarate <-> L-Glutamate + Indolepyruvate

L-Phenylalanine + 2-Oxoglutarate <-> L-Glutamate + Phenylpyruvate

L-Tyrosine + 2-Oxoglutarate <-> L-Glutamate + 3-(4-Hydroxyphenyl)pyruvate

L-Cysteine + 2-Oxoglutarate <-> Glutamate + 3-Mercaptopyruvate

L-Leucine + 2-Oxoglutarate <-> L-Glutamate + 4-Methyl-2-oxopentanoate