Enzyme Details

EC Classification

2.4.2.10

Enzyme name
(recommended)

orotate phosphoribosyltransferase

Alternative names

orotic acid phosphoribosyltransferase
orotidine-5'-phosphate:diphosphate phospho-alpha-D-ribosyl-transferase
orotidylic acid phosphorylase
orotidine-5'-phosphate pyrophosphorylase
OPRTase
orotate phosphoribosyl pyrophosphate transferase
orotidine 5'-monophosphate pyrophosphorylase
orotidine monophosphate pyrophosphorylase
orotidine phosphoribosyltransferase
orotidylate phosphoribosyltransferase
orotidylate pyrophosphorylase
orotidylic acid pyrophosphorylase
orotidylic phosphorylase
orotidylic pyrophosphorylase

Classification

Transferases

Glycosyltransferases

Pentosyltransferases

Catalyses reactions

Diphosphate + Orotidine 5'-phosphate <-> 5-Phospho-alpha-D-ribose 1-diphosphate + Orotate

Orotidine 5'-phosphate + Phosphonoacetate <-> Orotate + 5-Phospho-alpha-D-ribose 1-phosphonoacetate

Orotidine 5'-phosphate + Imidodiphosphate <-> Orotate + 5-Phospho-alpha-D-ribose 1-imidodiphosphate

Uracil + 5-Phospho-alpha-D-ribose 1-diphosphate <-> Diphosphate + Uridine 5'-phosphate

5-Phospho-alpha-D-ribose 1-diphosphate + Orotate 6'-methylester <-> Diphosphate + Orotidine 6'-methylester 5'-phosphate

Orotidine 5'-phosphate + Phosphonoformate <-> Orotate + 5-Phospho-alpha-D-ribose 1-phosphonoformate

5-Phospho-alpha-D-ribose 1-diphosphate + 5-Fluoroorotate <-> Diphosphate + 5-Fluoro-orotidine 5'-phosphate

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 2.4.2.10