Enzyme Details

 EC Classification 2.3.1.74
 Enzyme name
(recommended)
naringenin-chalcone synthase
 Alternative names malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
chalcone synthase
flavanone synthase
6'-deoxychalcone synthase
chalcone synthetase
DOCS
CHS
 Classification
Transferases
Acyltransferases
Acyltransferases
 Catalyses reactions
3 Malonyl-CoA + 4-Coumaroyl-CoA <-> 4 Coenzyme A + 3 CO2 + Naringenin chalcone
4-Coumaroyl-CoA <-> Isoliquiritigenin
3 Malonyl-CoA + Cinnamoyl-CoA <-> 4 Coenzyme A + 3 CO2 + (2RS)-4-Arsono-2-hydroxybutanoyl phosphate
3 Malonyl-CoA + Cinnamoyl diketide-NAC <-> 3 Coenzyme A + 3 CO2 + (2RS)-4-Arsono-2-hydroxybutanoyl phosphate + Gossylic nitrile 1,1'-diacetate
3 Malonyl-CoA + Benzyloxycarbonyl-alpha-L-glutamyl(gamma-glycineethylester)glycine <-> 4 CO2 + (2RS)-4-Arsono-2-hydroxybutanoyl phosphate + 3 Cinnamoyl-NAC + Gossylic nitrile 1,1'-diacetate
3 Malonyl-CoA + Cinnamoyl-CoA <-> 4 Coenzyme A + 3 CO2 + 2',4',6'-Trihydroxychalcone
3 Malonyl-CoA + Cinnamoyl-NAC <-> 3 Coenzyme A + 3 CO2 + 2',4',6'-Trihydroxychalcone + N-Acetylcysteamine
3 Malonyl-CoA + Cinnamoyl diketide-NAC <-> 3 Coenzyme A + 4 CO2 + 2',4',6'-Trihydroxychalcone + N-Acetylcysteamine
Malonyl-CoA <-> CO2 + Acetyl-CoA
Coenzyme A + Chalcone synthase <-> Enzyme-Coenzyme A complex
Acetyl-CoA + Chalcone synthase <-> Enzyme-Acetyl-CoA complex
4 Coenzyme A + 3 Malonyl-CoA + 3-Coumaroyl-CoA <-> 3 CO2 + 5,7,3''-Trihydroxyflavanone
3 Malonyl-CoA + 2-Coumaroyl-CoA <-> 4 Coenzyme A + 3 CO2 + 5,7,2''-Trihydroxyflavanone
3 Malonyl-CoA + Phenylpropionyl-CoA <-> 4 Coenzyme A + 3 CO2 + 3-Phenylpropionyl chalcone
3 Malonyl-CoA + 4-Methylcinnamoyl-CoA <-> Unknown + 4 Coenzyme A + 3 CO2
3 Malonyl-CoA + Feruloyl-CoA <-> 4 Coenzyme A + 3 CO2 + Homoeriodictyol chalcone
3 Malonyl-CoA + Phenylacetyl-CoA <-> Unknown + 4 Coenzyme A + 3 CO2
3 Malonyl-CoA + Benzoyl-CoA <-> Unknown + 4 Coenzyme A + 3 CO2
Acetyl-CoA + 2 Malonyl-CoA <-> 3 Coenzyme A + 2 CO2 + Triacetate lactone
3 Malonyl-CoA + Butanoyl-CoA <-> Unknown + 4 Coenzyme A + 3 CO2
3 Malonyl-CoA + n-Valeryl-CoA <-> Unknown + 4 Coenzyme A + 3 CO2
3 Malonyl-CoA + Hexanoyl-CoA <-> Unknown + 4 Coenzyme A + 3 CO2
3 Malonyl-CoA + Heptanoyl-CoA <-> Unknown + 4 Coenzyme A + 3 CO2
3 Malonyl-CoA + Octanoyl-CoA <-> Unknown + 4 Coenzyme A + 3 CO2
3 Malonyl-CoA + N-Methylanthraniloyl-CoA <-> H2O + 4 Coenzyme A + 3 CO2 + N-Methylanthraniloyltriacetic acid lactone
3 Malonyl-CoA + 4-Coumaroyl-CoA <-> 4 Coenzyme A + 3 CO2 + p-Coumaroyltriacetic acid lactone
 External links Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop


View all entries for EC Class: 2.3.1.74



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