Enzyme Details

EC Classification

2.3.1.16

Enzyme name
(recommended)

acetyl-CoA C-acyltransferase

Alternative names

KAT
beta-ketoadipyl coenzyme A thiolase
acyl-CoA:acetyl-CoA C-acyltransferase
beta-ketothiolase
3-ketoacyl-CoA thiolase
beta-ketoacyl coenzyme A thiolase
beta-ketoacyl-CoA thiolase
beta-ketoadipyl-CoA thiolase
3-ketoacyl CoA thiolase
3-ketoacyl coenzyme A thiolase
3-ketoacyl thiolase
3-ketothiolase
3-oxoacyl-CoA thiolase
3-oxoacyl-coenzyme A thiolase
6-oxoacyl-CoA thiolase
acetoacetyl-CoA beta-ketothiolase
acetyl-CoA acyltransferase
ketoacyl-CoA acyltransferase
ketoacyl-coenzyme A thiolase
long-chain 3-oxoacyl-CoA thiolase
oxoacyl-coenzyme A thiolase
pro-3-ketoacyl-CoA thiolase
thiolase I
2-methylacetoacetyl-CoA thiolase [misleading]

Classification

Transferases

Acyltransferases

Catalyses reactions

2 Acetyl-CoA <-> Coenzyme A + Acetoacetyl-CoA

Acetyl-CoA + Acyl-CoA <-> Coenzyme A + 3-Oxoacyl-CoA

Acetyl-CoA + Succinyl-CoA <-> Coenzyme A + 3-Oxoadipyl-CoA

Acetyl-CoA + Propanoyl-CoA <-> Coenzyme A + 2-Methylacetoacetyl-CoA

Acetyl-CoA + Butanoyl-CoA <-> Coenzyme A + 3-Oxohexanoyl-CoA

Propanoyl-CoA + Choloyl-CoA <-> Coenzyme A + 3alpha,7alpha,12alpha-Trihydroxy-5beta-24-oxocholestanoyl-CoA

Acetyl-CoA + Octanoyl-CoA <-> Coenzyme A + 3-Oxodecanoyl-CoA

Acetyl-CoA + Lauroyl-CoA <-> Coenzyme A + 3-Oxotetradecanoyl-CoA