Enzyme Details

EC Classification

2.1.2.10

Enzyme name
(recommended)

aminomethyltransferase

Alternative names

[protein]-S8-aminomethyldihydrolipoyllysine:tetrahydrofolate aminomethyltransferase (ammonia-forming)
S-aminomethyldihydrolipoylprotein:(6S)-tetrahydrofolate aminomethyltransferase (ammonia-forming)
T-protein
glycine synthase
tetrahydrofolate aminomethyltransferase
[protein]-8-S-aminomethyldihydrolipoyllysine:tetrahydrofolate aminomethyltransferase (ammonia-forming)

Classification

Transferases

Transferring one-carbon groups

Hydroxymethyl-, formyl- and related transferases

Catalyses reactions

NAD+ + Glycine + 5,6,7,8-Tetrahydrofolate <-> NADH + H+ + CO2 + NH3 + 5,10-Methylenetetrahydrofolate

5-Formyltetrahydrofolate <-> H2O + 5,10-Methenyltetrahydrofolate

5,6,7,8-Tetrahydrofolate + S-Aminomethyldihydrolipoylprotein <-> NH3 + 5,10-Methylenetetrahydrofolate + Dihydrolipoylprotein

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 2.1.2.10