Enzyme Details

EC Classification

2.1.1.107

Enzyme name
(recommended)

uroporphyrinogen-III C-methyltransferase

Alternative names

S-adenosyl-L-methionine:uroporphyrinogen-III C-methyltransferase
uroporphyrinogen methyltransferase
uroporphyrinogen-III methyltransferase
adenosylmethionine-uroporphyrinogen III methyltransferase
S-adenosyl-L-methionine-dependent uroporphyrinogen III methylase
uroporphyrinogen-III methylase
SirA
CysG
CobA [ambiguous - see EC 2.5.1.17] SUMT
uroporphyrin-III C-methyltransferase (incorrect)
S-adenosyl-L-methionine:uroporphyrin-III C-methyltransferase (incorrect)

Classification

Transferases

Transferring one-carbon groups

Methyltransferases

Catalyses reactions

2 S-Adenosyl-L-methionine + Uroporphyrinogen III <-> 2 S-Adenosyl-L-homocysteine + Precorrin 2

NAD+ + Precorrin 2 <-> NADH + H+ + Sirohydrochlorin

2 S-Adenosyl-L-methionine + Uroporphyrin III <-> 2 S-Adenosyl-L-homocysteine + Sirohydrochlorin

S-Adenosyl-L-methionine + Uroporphyrinogen III <-> S-Adenosyl-L-homocysteine + Precorrin 1

S-Adenosyl-L-methionine + Heptacarboxyporphyrinogen III <-> S-Adenosyl-L-homocysteine + Methylated heptacarboxyporphyrinogen III

S-Adenosyl-L-methionine + Hexacarboxyporphyrinogen III <-> S-Adenosyl-L-homocysteine + Methylated hexacarboxyporphyrinogen III

S-Adenosyl-L-methionine + Pentacarboxyporphyrinogen III <-> S-Adenosyl-L-homocysteine + Methylated pentacarboxyporphyrinogen III

S-Adenosyl-L-methionine + Uroporphyrinogen I <-> S-Adenosyl-L-homocysteine + Methylated uroporphyrinogen I

S-Adenosyl-L-methionine + Reduced chlorin <-> S-Adenosyl-L-homocysteine + Methylated reduced chlorin

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 2.1.1.107