Enzyme Details

EC Classification

1.6.99.1

Enzyme name
(recommended)

NADPH dehydrogenase

Alternative names

NADPH:acceptor oxidoreductase
NADPH2 diaphorase
NADPH diaphorase
OYE
diaphorase
dihydronicotinamide adenine dinucleotide phosphate dehydrogenase
NADPH-dehydrogenase
NADPH-diaphorase
NADPH2-dehydrogenase
old yellow enzyme
reduced nicotinamide adenine dinucleotide phosphate dehydrogenase
TPNH dehydrogenase
TPNH-diaphorase
triphosphopyridine diaphorase
triphosphopyridine nucleotide diaphorase
NADPH2 dehydrogenase
NADPH:(acceptor) oxidoreductase

Classification

Oxidoreductases

Acting on NADH or NADPH

With other acceptors

Catalyses reactions

H+ + NADPH + Acceptor <-> NADP+ + Reduced acceptor

H+ + NADPH + 2,4,6-Trinitrotoluene <-> NADP+ + Reduced 2,4,6-trinitrotoluene

H+ + NADPH + Cyclohex-2-enone <-> NADP+ + Cyclohexanone

H+ + NADPH + N-Ethylmaleimide <-> NADP+ + Reduced N-ethylmaleimide

H+ + NADPH + Nitroglycerin <-> NADP+ + Reduced nitroglycerin

H+ + NADPH + trans-2-Hexenal <-> NADP+ + Hexanal

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 1.6.99.1