Enzyme Details

 EC Classification 1.4.3.2
 Enzyme name
(recommended)
L-amino-acid oxidase
 Alternative names L-amino-acid:oxygen oxidoreductase (deaminating)
ophio-amino-acid oxidase
 Classification
Oxidoreductases
Acting on the CH-NH(2) group of donors
With oxygen as acceptor
 Catalyses reactions
H2O + L-Glutamate + O2 <-> NH3 + H2O2 + 2-Oxoglutarate
H2O + L-Aspartate + O2 <-> NH3 + H2O2 + Oxaloacetate
H2O + Glycine + O2 <-> NH3 + Glyoxylate + H2O2
H2O + L-Lysine + O2 <-> NH3 + H2O2 + 6-Amino-2-oxohexanoate
H2O + L-Arginine + O2 <-> NH3 + H2O2 + 5-Guanidino-2-oxopentanoate
H2O + L-Methionine + O2 <-> NH3 + H2O2 + 4-Methylthio-2-oxobutanoate
H2O + L-Tryptophan + O2 <-> NH3 + H2O2 + Indolepyruvate
H2O + L-Phenylalanine + O2 <-> NH3 + H2O2 + Phenylpyruvate
H2O + L-Tyrosine + O2 <-> NH3 + H2O2 + 3-(4-Hydroxyphenyl)pyruvate
H2O + O2 + L-Amino acid <-> NH3 + H2O2 + 2-Oxo acid
H2O + L-Isoleucine + O2 <-> NH3 + H2O2 + 3-Methyl-2-oxopentanoate
H2O + O2 + alpha-Amino acid <-> NH3 + H2O2 + 2-Oxo acid
H2O + L-Leucine + O2 <-> NH3 + H2O2 + 4-Methyl-2-oxopentanoate
H2O + O2 + L-alpha-Aminobutyrate <-> NH3 + H2O2 + 2-Oxobutyrate
H2O + L-Valine + O2 <-> NH3 + H2O2 + alpha-Ketovaline
H2O + O2 + S-Adenosyl-L-homocysteine <-> NH3 + H2O2 + 4-Thioadenosyl-2-oxobutyrate
H2O + O2 + L-Cystine <-> NH3 + H2O2 + 2-Oxo-2-amino-beta-dithiolactic acid
H2O + O2 + L-2,4-Diaminobutanoate <-> NH3 + H2O2 + 2-Oxo-4-aminobutyrate
H2O + L-Alanine + O2 <-> Pyruvate + NH3 + H2O2
H2O + L-Glutamine + O2 <-> NH3 + H2O2 + 2-Oxoglutaramate
H2O + L-Histidine + O2 <-> NH3 + H2O2 + 2-Oxo-3-[4-imidazolyl]-propanoate
H2O + O2 + L-Norleucine <-> NH3 + H2O2 + 2-Oxohexanoate
H2O + O2 + L-Glutamic acid-gamma-ethyl ester <-> NH3 + H2O2 + 2-Oxoglutarate-gamma-ethyl ester
H2O + O2 + L-Norvaline <-> NH3 + H2O2 + 2-Oxopentanoate
H2O + L-Asparagine + O2 <-> NH3 + H2O2 + 2-Oxosuccinamate
H2O + O2 + L-Ornithine <-> NH3 + H2O2 + 5-Amino-2-oxopentanoate
H2O + O2 + N-Acetyl-L-leucine <-> NH3 + H2O2 + N-Acetyl-4-methyl-2-oxopentanoate
H2O + O2 + 3,4-Dehydro-L-proline <-> NH3 + H2O2 + 2-Oxopent-3-enoate
H2O + O2 + L-Leucine methyl ester <-> NH3 + H2O2 + 4-Methyl-2-oxopentanoate methyl ester
H2O + L-Proline + O2 <-> NH3 + H2O2 + 2-Oxopentanoate
H2O + L-Serine + O2 <-> NH3 + H2O2 + 3-Hydroxypyruvate
H2O + 2 L-Cysteine + O2 <-> NH3 + H2O2 + 2 2-Oxo-3-thio-propanoate
 External links Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop


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