Enzyme Details

 EC Classification 1.3.98.1
 Enzyme name
(recommended)		 dihydroorotate dehydrogenase (fumarate)
 Alternative names (S)-dihydroorotate:fumarate oxidoreductase
DHOdehase (ambiguous)
dihydroorotate dehydrogenase (ambiguous)
dihydoorotic acid dehydrogenase (ambiguous)
DHOD (ambiguous)
DHODase (ambiguous)
dihydroorotate oxidase, pyr4 (gene name)
 Classification
Oxidoreductases
Acting on the CH-CH group of donors
With other, known, physiological acceptors
 Catalyses reactions
L-Dihydroorotate + Acceptor <-> Orotate + Reduced acceptor
2 NADH + 2 H+ + O2 <-> 2 NAD+ + 2 H2O
O2 + L-Dihydroorotate <-> H2O2 + Orotate
Fumarate + L-Dihydroorotate <-> Succinate + Orotate
L-Dihydroorotate + Decylubiquinone <-> Orotate + Decylubiquinol
L-Dihydroorotate + 2,6-Dichloroindophenol <-> Orotate + Reduced 2,6-dichlorophenolindophenol
L-Dihydroorotate + Menadione <-> Orotate + Menadiol
L-Dihydroorotate + Nitroblue tetrazolium <-> H+ + Orotate + Reduced nitroblue tetrazolium
Riboflavin-5-phosphate + L-Dihydroorotate <-> Orotate + Reduced FMN
Hexacyanoferrate(III) + L-Dihydroorotate <-> Orotate + Hexacyanoferrate(II)
Hexacyanoferrate(III) + Dihydro-5-azaorotic acid <-> Hexacyanoferrate(II) + 5-Azaorotic acid
L-Dihydroorotate + 2,3-Dimethoxy-5-methyl-1,4-benzoquinone <-> Orotate + 2,3-Dimethoxy-5-methyl-1,4-benzoquinol
 External links Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop


View all entries for EC Class: 1.3.98.1



© HITS gGmbH