Enzyme Details

 EC Classification 1.3.8.8
 Enzyme name
(recommended)
long-chain-acyl-CoA dehydrogenase
 Alternative names long-chain-acyl-CoA:acceptor 2,3-oxidoreductase
palmitoyl-CoA dehydrogenase
palmitoyl-coenzyme A dehydrogenase
long-chain acyl-coenzyme A dehydrogenase
long-chain-acyl-CoA:(acceptor) 2,3-oxidoreductase
 Classification
Oxidoreductases
Acting on the CH-CH group of donors
With a flavin as acceptor
 Catalyses reactions
Acyl-CoA + Acceptor <-> Reduced acceptor + 2,3-Dehydroacyl-CoA
FAD + Palmitoyl-CoA <-> FADH2 + trans-Hexadec-2-enoyl-CoA
FAD + Lauroyl-CoA <-> FADH2 + 2-trans-Dodecenoyl-CoA
FAD + Myristoyl-CoA <-> FADH2 + trans-Tetradec-2-enoyl-CoA
Decanoyl-CoA + Acceptor <-> trans-Dec-2-enoyl-CoA + Reduced acceptor
Lauroyl-CoA + Acceptor <-> 2-trans-Dodecenoyl-CoA + Reduced acceptor
Lauroyl-CoA + Acceptor <-> 2-trans-Dodecenoyl-CoA + Reduced acceptor
Decanoyl-CoA + Ferricenium hexafluorophosphate <-> trans-Dec-2-enoyl-CoA + Ferrocenium hexafluorophosphate
Hexanoyl-CoA + Ferricenium hexafluorophosphate <-> trans-Hex-2-enoyl-CoA + Ferrocenium hexafluorophosphate
Eicosanoyl-CoA + Ferricenium hexafluorophosphate <-> Ferrocenium hexafluorophosphate + trans-Eicos-2-enoyl-CoA
Palmitoyl-CoA + Ferricenium hexafluorophosphate <-> trans-Hexadec-2-enoyl-CoA + Ferrocenium hexafluorophosphate
Palmitoyl-CoA + Ferricenium hexafluorophosphate <-> trans-Hexadec-2-enoyl-CoA + Ferrocenium hexafluorophosphate
Lauroyl-CoA + Ferricenium hexafluorophosphate <-> 2-trans-Dodecenoyl-CoA + Ferrocenium hexafluorophosphate
Acceptor + all-cis-4,7,10,13-Hexadecatetraenoyl-CoA <-> Reduced acceptor + (2E,4Z,7Z,10Z,13Z)-Hexadecapentaenoyl-CoA
Acceptor + Stearoyl-CoA <-> Reduced acceptor + trans-2-Octadecenoyl-CoA
Myristoyl-CoA + Ferricenium hexafluorophosphate <-> trans-Tetradec-2-enoyl-CoA + Ferrocenium hexafluorophosphate
Myristoyl-CoA + Acceptor <-> trans-Tetradec-2-enoyl-CoA + Reduced acceptor
FAD + Stearoyl-CoA <-> FADH2 + trans-2-Octadecenoyl-CoA
FAD + Oleoyl-CoA <-> FADH2 + 2-trans-9-trans-Octadecendienoyl-CoA
FAD + Stearoyl-CoA <-> FADH2 + trans-2-Octadecenoyl-CoA
FAD + Palmitoyl-CoA <-> FADH2 + trans-Hexadec-2-enoyl-CoA
Palmitoyl-CoA + Acceptor <-> trans-Hexadec-2-enoyl-CoA + Reduced acceptor
FAD + Octanoyl-CoA <-> FADH2 + trans-Oct-2-enoyl-CoA
FAD + Lauroyl-CoA <-> FADH2 + 2-trans-Dodecenoyl-CoA
FAD + Myristoyl-CoA <-> FADH2 + trans-Tetradec-2-enoyl-CoA
FAD + Hexanoyl-CoA <-> FADH2 + trans-Hex-2-enoyl-CoA
FAD + Decanoyl-CoA <-> FADH2 + trans-Dec-2-enoyl-CoA
Hexanoyl-CoA + Acceptor <-> trans-Hex-2-enoyl-CoA + Reduced acceptor
Octanoyl-CoA + Acceptor <-> trans-Oct-2-enoyl-CoA + Reduced acceptor
Octanoyl-CoA + Ferricenium hexafluorophosphate <-> trans-Oct-2-enoyl-CoA + Ferrocenium hexafluorophosphate
Lauroyl-CoA + Ferricenium hexafluorophosphate <-> 2-trans-Dodecenoyl-CoA + Ferrocenium hexafluorophosphate
Acceptor + cis-Dec-6-enoyl-CoA <-> Reduced acceptor + trans,cis-2,6-Decadienoyl-CoA
Acceptor + cis-Dec-5-enoyl-CoA <-> Reduced acceptor + trans,cis-2,5-Decadienoyl-CoA
Acceptor + cis-Dec-4-enoyl-CoA <-> Reduced acceptor + trans,cis-2,4-Decadienoyl-CoA
Acceptor + cis,cis-4,7-Decadienoyl-CoA <-> Reduced acceptor + trans,cis,cis-2,4,7-Decatrienoyl-CoA
Acceptor + all-cis-4,7,10,13-Hexadecatetraenoyl-CoA <-> Reduced acceptor + (2E,4Z,7Z,10Z,13Z)-Hexadecapentaenoyl-CoA
Stearoyl-CoA + Ferricenium hexafluorophosphate <-> trans-Oct-2-enoyl-CoA + Ferrocenium hexafluorophosphate
Acceptor + Stearoyl-CoA <-> Reduced acceptor + trans-2-Octadecenoyl-CoA
Myristoyl-CoA + Ferricenium hexafluorophosphate <-> trans-Tetradec-2-enoyl-CoA + Ferrocenium hexafluorophosphate
Myristoyl-CoA + Acceptor <-> trans-Tetradec-2-enoyl-CoA + Reduced acceptor
Palmitoyl-CoA + Acceptor <-> trans-Hexadec-2-enoyl-CoA + Reduced acceptor
 External links Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop


View all entries for EC Class: 1.3.8.8



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