Enzyme Details

EC Classification

1.3.3.6

Enzyme name
(recommended)

acyl-CoA oxidase

Alternative names

acyl-CoA:oxygen 2-oxidoreductase
fatty acyl-CoA oxidase
acyl coenzyme A oxidase
fatty acyl-coenzyme A oxidase

Classification

Oxidoreductases

Acting on the CH-CH group of donors

With oxygen as acceptor

Catalyses reactions

O2 + Acyl-CoA <-> H2O2 + trans-2,3-Didehydroacyl-CoA

FAD + Butanoyl-CoA <-> Crotonoyl-CoA + FADH2

FAD + Palmitoyl-CoA <-> FADH2 + trans-Hexadec-2-enoyl-CoA

FAD + Octanoyl-CoA <-> FADH2 + trans-Oct-2-enoyl-CoA

FAD + Lauroyl-CoA <-> FADH2 + 2-trans-Dodecenoyl-CoA

FAD + Myristoyl-CoA <-> FADH2 + trans-Tetradec-2-enoyl-CoA

FAD + Hexanoyl-CoA <-> FADH2 + trans-Hex-2-enoyl-CoA

FAD + Decanoyl-CoA <-> FADH2 + trans-Dec-2-enoyl-CoA

O2 + Decanoyl-CoA <-> H2O2 + trans-Dec-2-enoyl-CoA

O2 + Lauroyl-CoA <-> H2O2 + 2-trans-Dodecenoyl-CoA

O2 + Linoleoyl-CoA <-> H2O2 + 2-trans-9-trans-12-trans-Octadecatrienoyl-CoA

O2 + Myristoyl-CoA <-> H2O2 + trans-Tetradec-2-enoyl-CoA

O2 + Octanoyl-CoA <-> H2O2 + trans-Oct-2-enoyl-CoA

O2 + Oleoyl-CoA <-> H2O2 + 2-trans-9-trans-Octadecendienoyl-CoA

O2 + Palmitoyl-CoA <-> H2O2 + trans-Hexadec-2-enoyl-CoA

O2 + Stearoyl-CoA <-> H2O2 + trans-2-Octadecenoyl-CoA

O2 + Hexanoyl-CoA <-> H2O2 + trans-Hex-2-enoyl-CoA

O2 + Eicosanoyl-CoA <-> H2O2 + trans-Eicos-2-enoyl-CoA

O2 + Butanoyl-CoA <-> H2O2 + Crotonoyl-CoA

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 1.3.3.6

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