Enzyme Details

EC Classification

1.3.1.1

Enzyme name
(recommended)

dihydropyrimidine dehydrogenase (NAD+)

Alternative names

5,6-dihydropyrimidine:NAD+ oxidoreductase
dihydropyrimidine dehydrogenase
dihydrothymine dehydrogenase
pyrimidine reductase
thymine reductase
uracil reductase
dihydrouracil dehydrogenase (NAD+)

Classification

Oxidoreductases

Acting on the CH-CH group of donors

With NAD(+) or NADP(+) as acceptor

Catalyses reactions

NAD+ + 5,6-Dihydrouracil <-> NADH + H+ + Uracil

NAD+ + 5,6-Dihydrothymine <-> NADH + H+ + Thymine

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 1.3.1.1