Enzyme Details

EC Classification

1.21.99.3

Enzyme name
(recommended)

thyroxine 5-deiodinase

Alternative names

type III iodothyronine deiodinase
acceptor:3,3',5'-triiodo-L-thyronine oxidoreductase (iodinating)
diiodothyronine 5'-deiodinase[ambiguous]
iodothyronine 5-deiodinase
iodothyronine inner ring monodeiodinase

Classification

Oxidoreductases

Acting on X-H and Y-H to form an X-Y bond

With other acceptors

Catalyses reactions

H+ + I- + Acceptor + 3,3',5'-Triiodothyronine <-> L-Thyroxine + Reduced acceptor

Reduced acceptor + Triiodothyronine <-> H+ + I- + Acceptor + 3,3'-Diiodothyronine

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 1.21.99.3