Enzyme Details

 EC Classification 1.14.15.18
 Enzyme name
(recommended)
calcidiol 1-monooxygenase
 Alternative names calcidiol,adrenodoxin:oxygen oxidoreductase (1-hydroxylating)
25-hydroxycholecalciferol 1-hydroxylase
25-hydroxycholecalciferol 1?-hydroxylase
25-hydroxyvitamin D3 1?-hydroxylase
25-hydroxycholecalciferol 1-monooxygenase
1-hydroxylase-25-hydroxyvitamin D3
25-hydroxy D3-1?-hydroxylase
calcidiol,NADPH:oxygen oxidoreductase (1-hydroxylating)
25-hydroxycholecalciferol 1-hydroxylase
25-hydroxycholecalciferol 1-monooxygenase
1-hydroxylase-25-hydroxyvitamin D3
25-hydroxy D3-1alpha-hydroxylase
25-hydroxycholecalciferol 1alpha-hydroxylase
25-hydroxyvitamin D3 1alpha-hydroxylase
 Classification
Oxidoreductases
Acting on paired donors with incorporation of molecular oxygen
With a reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen
 Catalyses reactions
H+ + NADPH + O2 + Calcidiol <-> H2O + NADP+ + Calcitriol
H+ + NADPH + O2 + Calcidiol <-> H2O + NADP+ + Calcitriol
 External links Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop


View all entries for EC Class: 1.14.15.18



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