Enzyme Details

 EC Classification 1.14.14.57
 Enzyme name
(recommended)		 taurochenodeoxycholate 6alpha-hydroxylase
 Alternative names taurochenodeoxycholate,NADPH:oxygen oxidoreductase (6alpha-hydroxylating)
CYP3A4
CYP4A21
taurochenodeoxycholate 6alpha-monooxygenase
 Classification
Oxidoreductases
Acting on paired donors with incorporation of molecular oxygen
With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
 Catalyses reactions
L-Cysteine + Sulfite <-> Hydrogen sulfide + L-Cysteate
H+ + NADPH + O2 + Testosterone <-> H2O + NADP+ + 6beta-Hydroxytestosterone
H+ + NADPH + O2 + 3,5-Dihydroxy-4'-O-methoxystilbene <-> H2O + NADP+ + Trihydroxy-4'-O-methoxystilbene
H+ + NADPH + O2 + 5,4'-Dihydroxy-3-O-methoxystilbene <-> H2O + NADP+ + Trihydroxy-3-O-methoxystilbene
H+ + NADPH + O2 + Piceid <-> H2O + NADP+ + Tetrahydroxystilbene-3-beta-monoglucoside
H+ + NADPH + O2 + 3,4',5-Trihydroxystilbene <-> H2O + NADP+ + Tetrahydroxystilbene
H+ + NADPH + O2 + Resveratroloside <-> H2O + NADP+ + Trihydroxystilbene-4'-O-beta-D-glucopyranoside
 External links Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop


View all entries for EC Class: 1.14.14.57



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