Enzyme Details

EC Classification

1.14.14

Enzyme name
(recommended)

With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

Classification

Oxidoreductases

Acting on paired donors with incorporation of molecular oxygen

With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

Catalyses reactions

H+ + NADPH + O2 + Phenacetin <-> H2O + Ethanol + NADP+ + Acetaminophen

H+ + NADPH + O2 + Omeprazole <-> Unknown + H2O + NADP+

H+ + NADPH + O2 + Chlorzoxazone <-> H2O + NADP+ + 6-Hydroxy-chlorzoxazone

H+ + NADPH + O2 + Flucloxacillin <-> H2O + NADP+ + 5-Hydroxymethylflucloxacillin

H+ + NADPH + O2 + Diclofenac <-> H2O + NADP+ + 4'-Hydroxydiclofenac

2 NADH + H+ + O2 + 2,4,5-Trichlorophenol <-> Cl- + 2 NAD+ + OH- + 2,5-Dichlorohydroquinone

2 NADH + H+ + O2 + 2,4,6-Trichlorophenol <-> Cl- + 2 NAD+ + OH- + 2,6-Dichlorohydroquinone

FADH2 + FADH2-dependent monooxygenase <-> Enzyme-FADH2 complex

H+ + NADPH + O2 + Geissoschizine <-> 2 H2O + NADP+ + Polyneuridine aldehyde

H+ + NADPH + O2 + Tetrahydroalstonine <-> 2 H2O + NADP+ + Alstonine

H+ + NADPH + O2 + Tabersonine <-> H2O + NADP+ + Lochnericine

Guaiacol + GcoA <-> Enzyme-ligand complex

3-Methoxycatechol + GcoA <-> Enzyme-ligand complex

Anisole + GcoA <-> Enzyme-ligand complex

Guaethol + GcoA <-> Enzyme-ligand complex

2-Methylanisole + GcoA <-> Enzyme-ligand complex

4-Hydroxy-3-methoxy-benzaldehyde + GcoA <-> Enzyme-ligand complex

2,6-Dimethoxyphenol + GcoA <-> Enzyme-ligand complex

H+ + NADPH + O2 + 3beta-Hydroxyandrost-5-en-17-one <-> H2O + NADP+ + 3beta,7alpha-Dihydroxyandrost-5-en-17-one

H+ + NADPH + O2 + Pregnenolone <-> H2O + NADP+ + 7alpha-Hydroxypregnenolone

H+ + NADPH + O2 + Estradiol-17beta <-> H2O + NADP+ + 7alpha-Hydroxyestradiol

NADH + H+ + O2 + 4-Hydroxyphenylacetate <-> NAD+ + H2O + 3,4-Dihydroxyphenylacetate

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 1.14.14

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