Enzyme Details
EC Classification
1.14.13.84
Enzyme name
(recommended)
4-hydroxyacetophenone monooxygenase
Alternative names
(4-hydroxyphenyl)ethan-1-one,NADPH:oxygen oxidoreductase (ester-forming)
HAPMO
Classification
Oxidoreductases
Acting on paired donors with incorporation of molecular oxygen
With NADH or NADPH as one donor, and incorporation of one atom of oxygen
Catalyses reactions
H+ + NADPH + O2 + 4'-Hydroxyacetophenone <-> H2O + NADP+ + 4-Hydroxyphenylacetate
H+ + NADPH + O2 + 4-Hydroxypropiophenone <-> H2O + NADP+ + (4-Hydroxyphenyl)propionate
H+ + NADPH + O2 + 4-Aminoacetophenone <-> H2O + NADP+ + (4-Aminophenyl)acetate
H+ + NADPH + O2 + 2-Hydroxyacetophenone <-> H2O + NADP+ + 2-Hydroxyphenylacetate
H+ + NADPH + O2 + 3-Hydroxyacetophenone <-> H2O + NADP+ + 3-Hydroxyphenylacetate
H+ + NADPH + O2 + Benzaldehyde <-> H2O + NADP+ + Benzoate
H+ + NADPH + O2 + Acetophenone <-> H2O + NADP+ + Phenylacetic acid
H+ + NADPH + O2 + Propiophenone <-> H2O + NADP+ + Phenyl propionate
H+ + NADPH + O2 + Butyrophenone <-> H2O + NADP+ + Phenyl butyrate
H+ + NADPH + O2 + Isobutyrophenone <-> H2O + NADP+ + Phenyl isobutyrate
H+ + NADPH + O2 + Methylphenyl sulfide <-> H2O + NADP+ + Methyl phenyl sulfoxide
H+ + NADPH + O2 + 2-Acetylpyridine <-> Unknown + H2O + NADP+
H+ + NADPH + O2 + 4-Acetylpyridine <-> Unknown + H2O + NADP+
H+ + NADPH + O2 + 2-Acetylpyrrole <-> H2O + NADP+ + 1H-pyrrol-2-yl acetate
H+ + NADPH + O2 + 2-Pyrrole carboxaldehyde <-> Unknown + H2O + NADP+
H+ + NADPH + O2 + Acetylcyclohexane <-> Unknown + H2O + NADP+
H+ + NADPH + O2 + Cyclohexane carboxaldehyde <-> Unknown + H2O + NADP+
H+ + NADPH + O2 + Hydroxyacetone <-> Unknown + H2O + NADP+
H+ + NADPH + O2 + 3-Chloro-2-butanone <-> Unknown + H2O + NADP+
H+ + NADPH + O2 + 2,4-Pentanedione <-> Unknown + H2O + NADP+
H+ + NADPH + O2 + Bicyclohept-2-en-6-one <-> Unknown + H2O + NADP+
H+ + NADPH + O2 + 4-Methylacetophenone <-> H2O + NADP+ + Tolylacetate
H+ + NADPH + O2 + 4-Methoxyacetophenone <-> H2O + NADP+ + 4-Methoxyphenyl acetate
H+ + NADPH + O2 + 4-Fluoroacetophenone <-> H2O + NADP+ + 4-Fluorophenyl acetate
H+ + NADPH + O2 + 4-Hydroxy-3-methylacetophenone <-> H2O + NADP+ + 4-Hydroxy-3-methylphenyl acetate
H+ + NADPH + O2 + 4-Hydroxybenzaldehyde <-> Unknown + H2O + NADP+
NADPH + O2 + Methyl 4-tolyl sulfide <-> H2O + NADP+ + Methyl 4-tolyl sulfoxide
NAD+ + 1-(4'-Hydroxyphenyl)ethanol <-> NADH + H+ + 4'-Hydroxyacetophenone
External links
Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop
View all entries for EC Class:
1.14.13.84
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