Enzyme Details
EC Classification
1.14.12.17
Enzyme name
(recommended)
nitric oxide dioxygenase
Alternative names
nitric oxide,NAD(P)H:oxygen oxidoreductase
Classification
Oxidoreductases
Acting on paired donors with incorporation of molecular oxygen
With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor
Catalyses reactions
NADH + H+ + H2O2 <-> NAD+ + 2 H2O
NADH + 2 O2 + 2 Nitric oxide <-> NAD+ + H+ + 2 Nitrate
NADPH + 2 O2 + 2 Nitric oxide <-> H+ + NADP+ + 2 Nitrate
NADH + H+ + Cumene hydroperoxide <-> NAD+ + H2O + 2-Phenyl-2-propanol
NADH + H+ + t-Butylhydroperoxide <-> NAD+ + H2O + t-Butanol
NADH + H+ + (9Z,11E)-(13S)-13-Hydroperoxyoctadeca-9,11-dienoate <-> NAD+ + H2O + 13(S)-HODE
NAD+ + 2 Fe2+ <-> NADH + H+ + 2 Fe3+
NADH + S-Nitrosoglutathione <-> NAD+ + Glutathione sulfinamide
NADH + H+ + Cytochrome c <-> NAD+ + Reduced cytochrome c
NADH + H+ + Nitrite <-> NAD+ + H2O + Nitric oxide
External links
Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop
View all entries for EC Class:
1.14.12.17
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