Enzyme Details

EC Classification

1.1.99.2

Enzyme name
(recommended)

2-hydroxyglutarate dehydrogenase

Alternative names

(S)-2-hydroxyglutarate:acceptor 2-oxidoreductase
alpha-ketoglutarate reductase
alpha-hydroxyglutarate dehydrogenase
L-alpha-hydroxyglutarate dehydrogenase
hydroxyglutaric dehydrogenase
alpha-hydroxyglutarate oxidoreductase
L-alpha-hydroxyglutarate:NAD+ 2-oxidoreductase
alpha-hydroxyglutarate dehydrogenase (NAD+ specific)
(S)-2-hydroxyglutarate:(acceptor) 2-oxidoreductase

Classification

Oxidoreductases

Acting on the CH-OH group of donors

With other acceptors

Catalyses reactions

(S)-2-Hydroxyglutarate + Acceptor <-> 2-Oxoglutarate + Reduced acceptor

FAD + 2-Hydroxyglutarate <-> 2-Oxoglutarate + FADH2

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 1.1.99.2