Enzyme Details

EC Classification

1.1.1.41

Enzyme name
(recommended)

isocitrate dehydrogenase (NAD+)

Alternative names

isocitrate:NAD+ oxidoreductase (decarboxylating)
isocitric dehydrogenase
beta-ketoglutaric-isocitric carboxylase
isocitric acid dehydrogenase
NAD dependent isocitrate dehydrogenase
NAD isocitrate dehydrogenase
NAD-linked isocitrate dehydrogenase
NAD-specific isocitrate dehydrogenase
NAD isocitric dehydrogenase
isocitrate dehydrogenase (NAD)
IDH (ambiguous)
nicotinamide adenine dinucleotide isocitrate dehydrogenase

Classification

Oxidoreductases

Acting on the CH-OH group of donors

With NAD(+) or NADP(+) as acceptor

Catalyses reactions

NAD+ + Isocitrate <-> NADH + H+ + CO2 + 2-Oxoglutarate

Isocitrate + thio-NAD+ <-> H+ + CO2 + 2-Oxoglutarate + thio-NADH

NAD+ + D-threo-Isocitrate <-> NADH + CO2 + 2-Oxoglutarate

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 1.1.1.41