Enzyme Details

 EC Classification 1.1.1.291
 Enzyme name
(recommended)		 2-hydroxymethylglutarate dehydrogenase
 Alternative names (S)-2-hydroxymethylglutarate:NAD+ oxidoreductase
HgD
 Classification
Oxidoreductases
Acting on the CH-OH group of donors
With NAD(+) or NADP(+) as acceptor
 Catalyses reactions
NAD+ + (S)-2-(Hydroxymethyl)glutarate <-> NADH + H+ + (S)-2-Formylglutarate
NAD+ + L-Serine <-> NADH + H+ + L-2-Amino-3-oxopropionate
NAD+ + L-Glycerate <-> NADH + H+ + 3-Hydroxypyruvate
NAD+ + (S)-3-Hydroxyisobutyrate <-> NADH + H+ + (S)-Methylmalonate semialdehyde
NAD+ + 2-(Hydroxymethyl)glutarate <-> NADH + 2-Formylglutarate
 External links Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop


View all entries for EC Class: 1.1.1.291



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