Enzyme Details

EC Classification

1.1.1.178

Enzyme name
(recommended)

3-hydroxy-2-methylbutyryl-CoA dehydrogenase

Alternative names

(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA:NAD+ oxidoreductase
2-methyl-3-hydroxybutyryl coenzyme A dehydrogenase
2-methyl-3-hydroxybutyryl coenzyme A dehydrogenase
2-methyl-3-hydroxy-butyryl CoA dehydrogenase

Classification

Oxidoreductases

Acting on the CH-OH group of donors

With NAD(+) or NADP(+) as acceptor

Catalyses reactions

NAD+ + (S)-3-Hydroxybutanoyl-CoA <-> NADH + H+ + Acetoacetyl-CoA

NAD+ + (2S,3S)-3-Hydroxy-2-methylbutanoyl-CoA <-> NADH + H+ + 2-Methylacetoacetyl-CoA

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 1.1.1.178