Enzyme Details

EC Classification

1.1.1.170

Enzyme name
(recommended)

sterol-4alpha-carboxylate 3-dehydrogenase (decarboxylating)

Alternative names

3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate:NAD(P)+ 3-oxidoreductase (decarboxylating)
3beta-hydroxy-4beta-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating)
3beta-hydroxy-4beta-methylcholestenoate dehydrogenase
3beta-hydroxy-4beta-methylcholestenoate dehydrogenase
sterol 4alpha-carboxylic decarboxylase

Classification

Oxidoreductases

Acting on the CH-OH group of donors

With NAD(+) or NADP(+) as acceptor

Catalyses reactions

4 H2O + 3 NADP+ + CO2 + 5alpha-Cholest-8-en-3beta-ol <-> 3 H+ + 3 NADPH + 3 O2 + Methostenol

NAD+ + 3beta-Hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate <-> NADH + H+ + CO2 + 4alpha-Methyl-5alpha-cholest-7-en-3-one

6 H+ + 6 NADPH + 6 O2 + 14-Demethyllanosterol <-> 8 H2O + 6 NADP+ + 2 CO2 + Zymosterol

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 1.1.1.170