Enzyme Details

 EC Classification 1.1.1.159
 Enzyme name
(recommended)		 7alpha-hydroxysteroid dehydrogenase
 Alternative names 7alpha-hydroxysteroid:NAD+ 7-oxidoreductase
7alpha-hydroxy steroid dehydrogenase
7alpha-HSDH
 Classification
Oxidoreductases
Acting on the CH-OH group of donors
With NAD(+) or NADP(+) as acceptor
 Catalyses reactions
NAD+ + 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholanate <-> NADH + H+ + 3alpha,12alpha-Dihydroxy-7-oxo-5beta-cholanate
NADP+ + 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholanate <-> H+ + NADPH + 3alpha,12alpha-Dihydroxy-7-oxo-5beta-cholanate
NADP+ + Chenodeoxycholate <-> H+ + NADPH + 3alpha-Hydroxy-7-oxo-5beta-cholanate
NAD+ + Chenodeoxycholate <-> NADH + H+ + 3alpha-Hydroxy-7-oxo-5beta-cholanate
 External links Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop


View all entries for EC Class: 1.1.1.159



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