| EC Classification |
1.1.1.145
|
Enzyme name
(recommended) |
3beta-hydroxy-Delta5-steroid dehydrogenase |
| Alternative names |
3beta-hydroxy-Delta5-steroid:NAD+ 3-oxidoreductase
progesterone reductase
Delta5-3beta-hydroxysteroid dehydrogenase
3beta-hydroxy-5-ene steroid dehydrogenase
3beta-hydroxy steroid dehydrogenase/isomerase
3beta-hydroxy-Delta5-C27-steroid dehydrogenase/isomerase
3beta-hydroxy-Delta5-C27-steroid oxidoreductase
3beta-hydroxy-5-ene-steroid oxidoreductase
steroid-Delta5-3beta-ol dehydrogenase
3beta-HSDH
5-ene-3-beta-hydroxysteroid dehydrogenase
3beta-hydroxy-5-ene-steroid dehydrogenase
|
| Classification |
| Oxidoreductases |
| Acting on the CH-OH group of donors |
| With NAD(+) or NADP(+) as acceptor |
|
| Catalyses reactions
|
| NAD+ + 3beta-Hydroxyandrost-5-en-17-one <-> NADH + H+ + Androst-4-ene-3,17-dione |
| NADP+ + 3beta-Hydroxyandrost-5-en-17-one <-> H+ + NADPH + Androst-4-ene-3,17-dione |
| NAD+ + Pregnenolone <-> NADH + H+ + Progesterone |
| NADP+ + Pregnenolone <-> H+ + NADPH + Progesterone |
| NADH + H+ + Testosterone <-> NAD+ + Androst-5-ene-3beta,17beta-diol |
| NADH + H+ + Cortisol <-> NAD+ + 11beta,17alpha,21-Trihydroxypregnenolone |
| NAD+ + 3beta-Hydroxy-delta5-steroid <-> NADH + H+ + 3-Oxo-delta5-steroid |
| NAD+ + 17alpha-Hydroxypregnenolone <-> NADH + H+ + 17alpha-Hydroxyprogesterone |
| NADP+ + 17alpha-Hydroxypregnenolone <-> H+ + NADPH + 17alpha-Hydroxyprogesterone |
| NAD+ + 21-Hydroxypregnenolone <-> NADH + H+ + 11-Deoxycorticosterone |
| NADP+ + 21-Hydroxypregnenolone <-> H+ + NADPH + 11-Deoxycorticosterone |
| NADH + H+ + 16alpha-Hydroxyandrost-4-ene-3,17-dione <-> NAD+ + 16alpha-Hydroxydehydroepiandrosterone |
| H+ + NADPH + 16alpha-Hydroxyandrost-4-ene-3,17-dione <-> NADP+ + 16alpha-Hydroxydehydroepiandrosterone |
| NADH + H+ + 11-Deoxycortisol <-> NAD+ + 17alpha,21-Dihydroxypregnenolone |
| NAD+ + 3beta-Hydroxyandrost-5-en-17-one <-> NADH + H+ + Androst-5-ene-3,17-dione |
| NADP+ + 3beta-Hydroxyandrost-5-en-17-one <-> H+ + NADPH + Androst-5-ene-3,17-dione |
| NADH + H+ + 5beta-Androstane-17beta-ol-3-one <-> NAD+ + Androstanediol |
|
| External links
|
Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop
|
|
View all entries for EC Class:
1.1.1.145
|
