Enzyme Details

EC Classification

1.1.1.100

Enzyme name
(recommended)

3-oxoacyl-[acyl-carrier-protein] reductase

Alternative names

(3R)-3-hydroxyacyl-[acyl-carrier protein]:NADP+ oxidoreductase
beta-ketoacyl-[acyl-carrier protein](ACP) reductase
beta-ketoacyl acyl carrier protein (ACP) reductase
beta-ketoacyl reductase
beta-ketoacyl thioester reductase
beta-ketoacyl-ACP reductase
beta-ketoacyl-acyl carrier protein reductase
3-ketoacyl acyl carrier protein reductase
NADPH-specific 3-oxoacyl-[acylcarrier protein]reductase
3-oxoacyl-[ACP]reductase
(3R)-3-hydroxyacyl-[acyl-carrier-protein]:NADP+ oxidoreductase

Classification

Oxidoreductases

Acting on the CH-OH group of donors

With NAD(+) or NADP(+) as acceptor

Catalyses reactions

NADP+ + (3R)-3-Hydroxyacyl-[acyl-carrier protein] <-> H+ + NADPH + 3-Oxoacyl-[acyl-carrier protein]

NADP+ + (3R)-3-Hydroxybutanoyl-[acyl-carrier protein] <-> H+ + NADPH + Acetoacetyl-[acp]

NADP+ + (3R)-3-Hydroxydecanoyl-[acyl-carrier protein] <-> H+ + NADPH + 3-Oxodecanoyl-[acp]

NADP+ + (3R)-3-Hydroxyoctanoyl-[acyl-carrier protein] <-> H+ + NADPH + 3-Oxooctanoyl-[acp]

NADP+ + (3R)-3-Hydroxypalmitoyl-[acyl-carrier protein] <-> H+ + NADPH + 3-Oxohexadecanoyl-[acp]

NADP+ + (3R)-3-Hydroxytetradecanoyl-[acyl-carrier protein] <-> H+ + NADPH + 3-Oxotetradecanoyl-[acp]

NADP+ + (R)-3-Hydroxyhexanoyl-[acp] <-> H+ + NADPH + 3-Oxohexanoyl-[acp]

NADP+ + (R)-3-Hydroxydodecanoyl-[acp] <-> H+ + NADPH + 3-Oxododecanoyl-[acp]

NADP+ + 3-Hydroxybutanoyl-CoA <-> H+ + NADPH + Acetoacetyl-CoA

NADP+ + (R)-3-Hydroxybutanoyl-CoA <-> H+ + NADPH + Acetoacetyl-CoA

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 1.1.1.100